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Spectroscopic and Computational Investigation of Iron(III) Cysteine Dioxygenase: Implications for the Nature of the Putative Superoxo-Fe(III) Intermediate

[Image: see text] Cysteine dioxygenase (CDO) is a mononuclear, non-heme iron-dependent enzyme that converts exogenous cysteine (Cys) to cysteine sulfinic acid using molecular oxygen. Although the complete catalytic mechanism is not yet known, several recent reports presented evidence for an Fe(III)-...

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Detalhes bibliográficos
Main Authors: Blaesi, Elizabeth J., Fox, Brian G., Brunold, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165443/
https://ncbi.nlm.nih.gov/pubmed/25093959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500767x
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