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Spectroscopic insights into axial ligation and active-site H-bonding in substrate-bound human heme oxygenase-2

Heme oxygenases (HOs) are monooxygenases that catalyze the first step in heme degradation, converting heme to biliverdin with concomitant release of Fe(II) and CO from the porphyrin macrocycle. Two heme oxygenase isoforms, HO-1 and HO-2, exist that differ in several ways, including a complete lack o...

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Main Authors: Gardner, Jessica D., Yi, Li, Ragsdale, Stephen W., Brunold, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972362/
https://ncbi.nlm.nih.gov/pubmed/20502928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-010-0672-8
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