A Phase II Trial of Fosbretabulin in Advanced Anaplastic Thyroid Carcinoma and Correlation of Baseline Serum-Soluble Intracellular Adhesion Molecule-1 with Outcome

BACKGROUND: Fosbretabulin is a novel vascular-disrupting agent that has antitumor activity against anaplastic thyroid cancer (ATC) cell lines, xenografts, and demonstrable efficacy in a phase I trial. This phase II study determined the efficacy and safety of fosbretabulin in patients with advanced A...

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Bibliografische gegevens
Hoofdauteurs: Mooney, Colin J., Nagaiah, Govardhanan, Fu, Pingfu, Wasman, Jay K., Cooney, Matthew M., Savvides, Panos S., Bokar, Joseph A., Dowlati, Afshin, Wang, Ding, Agarwala, Sanjiv S., Flick, Susan M., Hartman, Paul H., Ortiz, Jose D., Lavertu, Pierre N., Remick, Scot C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2009
Onderwerpen:
Original Studies, Reviews and Scholarly Dialog
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913806/
https://ncbi.nlm.nih.gov/pubmed/19265494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2008.0321
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