A Phase II Trial of Fosbretabulin in Advanced Anaplastic Thyroid Carcinoma and Correlation of Baseline Serum-Soluble Intracellular Adhesion Molecule-1 with Outcome

BACKGROUND: Fosbretabulin is a novel vascular-disrupting agent that has antitumor activity against anaplastic thyroid cancer (ATC) cell lines, xenografts, and demonstrable efficacy in a phase I trial. This phase II study determined the efficacy and safety of fosbretabulin in patients with advanced A...

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Main Authors: Mooney, Colin J., Nagaiah, Govardhanan, Fu, Pingfu, Wasman, Jay K., Cooney, Matthew M., Savvides, Panos S., Bokar, Joseph A., Dowlati, Afshin, Wang, Ding, Agarwala, Sanjiv S., Flick, Susan M., Hartman, Paul H., Ortiz, Jose D., Lavertu, Pierre N., Remick, Scot C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Mary Ann Liebert, Inc. 2009
נושאים:
Original Studies, Reviews and Scholarly Dialog
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913806/
https://ncbi.nlm.nih.gov/pubmed/19265494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2008.0321
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