A Phase II Trial of Fosbretabulin in Advanced Anaplastic Thyroid Carcinoma and Correlation of Baseline Serum-Soluble Intracellular Adhesion Molecule-1 with Outcome

BACKGROUND: Fosbretabulin is a novel vascular-disrupting agent that has antitumor activity against anaplastic thyroid cancer (ATC) cell lines, xenografts, and demonstrable efficacy in a phase I trial. This phase II study determined the efficacy and safety of fosbretabulin in patients with advanced A...

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Detalhes bibliográficos
Main Authors: Mooney, Colin J., Nagaiah, Govardhanan, Fu, Pingfu, Wasman, Jay K., Cooney, Matthew M., Savvides, Panos S., Bokar, Joseph A., Dowlati, Afshin, Wang, Ding, Agarwala, Sanjiv S., Flick, Susan M., Hartman, Paul H., Ortiz, Jose D., Lavertu, Pierre N., Remick, Scot C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Original Studies, Reviews and Scholarly Dialog
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913806/
https://ncbi.nlm.nih.gov/pubmed/19265494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2008.0321
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