Loading...
Rbx1 Flexible Linker Facilitates Cullin-RING Ligase Function Before Neddylation and After Deneddylation
In ubiquitination, cullin-RING E3 ubiquitin ligases (CRLs) assist in ubiquitin transfer from ubiquitin-conjugating enzyme E2 to the substrate. Neddylation, which involves NEDD8 transfer from E2 to E3-cullin, stimulates ubiquitination by inducing conformational change in CRLs. However, deneddylation,...
Na minha lista:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2010
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913186/ https://ncbi.nlm.nih.gov/pubmed/20682250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.021 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|