ロード中...
Molecular dynamics reveal the essential role of linker motions in the function of cullin-RING E3 ligases
Tagging proteins by polyubiquitin is a key step in protein degradation. Cullin-RING E3 ubiquitin ligases (CRLs) facilitate ubiquitin transfer from the E2 conjugating enzyme to the substrate; yet, crystallography indicates a large distance between the E2 and the substrate, raising the question of how...
保存先:
| 主要な著者: | , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824043/ https://ncbi.nlm.nih.gov/pubmed/20083119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.022 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|