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Interaction Kinetics of Oximes with Native, Phosphylated and Aged Human Acetylcholinesterase
Oximes are commonly used nucleophilic reactivators of alkyl phosphorylated and alkyl methylphosphonylated acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). Covalent inhibition of these enzymes by organophosphate (OP) pesticides results typically in phosphorylated enzymes, while covalent...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912944/ https://ncbi.nlm.nih.gov/pubmed/20412789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.04.014 |
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