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Formation of aminyl radicals on electron attachment to AZT: Abstraction from the sugar phosphate backbone vs. one-electron oxidation of Guanine
Employing electron spin resonance (ESR) spectroscopy, we have characterized the radicals formed in 3′-Azido-3′-deoxythymidine (3′-AZT) and in its 5′-analog 5′-azido-5′-deoxythymidine (5′-AZT) after electron attachment in γ-irradiated aqueous (H(2)O or D(2)O) glassy (7.5 M LiCl) systems. ESR spectral...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912441/ https://ncbi.nlm.nih.gov/pubmed/20575557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp103403p |
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