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Highly Oxidizing Excited States of One-Electron Oxidized Guanine in DNA: Wavelength and pH Dependence

Excited states of one-electron oxidized guanine in DNA are known to induce hole transfer to the sugar moiety and on deprotonation result in neutral sugar radicals that are precursors of DNA-strand breaks. This work carried out in homogeneous aqueous glass (7.5 M LiCl) at low temperatures (77 to 175...

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Detalhes bibliográficos
Main Authors: Khanduri, Deepti, Adhikary, Amitava, Sevilla, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063320/
https://ncbi.nlm.nih.gov/pubmed/21381665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja110499a
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