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Prototropic Equilibria in DNA Containing One-electron Oxidized GC: Intra-duplex vs. Duplex to Solvent Deprotonation

By use of ESR and UV-vis spectral studies, this work identifies the protonation states of one-electron oxidized G:C (viz. G•(+):C, G(N1-H)•:C(+H(+)), G(N1-H)•:C, and G(N2-H)•:C) in a DNA oligomer d[TGCGCGCA](2.) Benchmark ESR and UV-vis spectra from one electron oxidized 1-Me-dGuo are employed to an...

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Publicat a:Phys Chem Chem Phys
Autors principals: Adhikary, Amitava, Kumar, Anil, Munafo, Shawn A., Khanduri, Deepti, Sevilla, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677782/
https://ncbi.nlm.nih.gov/pubmed/21491657
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