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HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes

HLA-DM catalyzes peptide dissociation and exchange in class II MHC molecules through a mechanism that has been proposed to involve disruption of specific components of the conserved hydrogen bond network in MHC-peptide complexes. HLA-DR1 molecules with alanine substitutions at each of the six conser...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Zhou, Zemin, Callaway, Kari A., Weber, Dominique A., Jensen, Peter E.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912111/
https://ncbi.nlm.nih.gov/pubmed/19767569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901663
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