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HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes
HLA-DM catalyzes peptide dissociation and exchange in class II MHC molecules through a mechanism that has been proposed to involve disruption of specific components of the conserved hydrogen bond network in MHC-peptide complexes. HLA-DR1 molecules with alanine substitutions at each of the six conser...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912111/ https://ncbi.nlm.nih.gov/pubmed/19767569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901663 |
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