ロード中...

HLA-DM targets the hydrogen bond between the histidine at position β81 and peptide to dissociate HLA-DR–peptide complexes

The peptide editor HLA-DM (DM) mediates exchange of peptides bound to major histocompatibility (MHC) class II molecules during antigen processing; however, the mechanism by which DM displaces peptides remains unclear. Here we generated a soluble mutant HLA-DR1 with a histidine-to-asparagine substitu...

詳細記述

保存先:
書誌詳細
主要な著者: Narayan, Kedar, Chou, Chih-Ling, Kim, AeRyon, Hartman, Isamu Z, Dalai, Sarat, Khoruzhenko, Stanislav, Sadegh-Nasseri, Scheherazade
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019572/
https://ncbi.nlm.nih.gov/pubmed/17143275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1414
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!