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HLA-DM mediates peptide exchange by interacting transiently and repeatedly with HLA-DR1
The peptide editor HLA-DM (DM) catalyzes the exchange of peptides bound to MHC class II molecules within antigen presenting cells by generating a “peptide-receptive” MHC class II conformation (MHC(receptive)) to which peptides readily bind and rapidly unbind. While recent work has uncovered the dete...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743474/ https://ncbi.nlm.nih.gov/pubmed/19647320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.07.001 |
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