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The love and hate relationship of HLA-DM/DO in the selection of immunodominant epitopes

Successful activation of CD4 T cells is centered around the ability of antigen presenting cells to successfully process, select Class II immunodominant epitopes from exogenous antigens and to present it to cognate T cells. To achieve this, newly synthesized MHC-II molecules are transferred to a spec...

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Veröffentlicht in:Curr Opin Immunol
Hauptverfasser: Welsh, Robin A., Sadegh-Nasseri, Scheherazade
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762731/
https://ncbi.nlm.nih.gov/pubmed/32599219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2020.05.007
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