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HLA-DO as the Optimizer of Epitope Selection for MHC Class II Antigen Presentation
Processing of antigens for presentation to helper T cells by MHC class II involves HLA-DM (DM) and HLA-DO (DO) accessory molecules. A mechanistic understanding of DO in this process has been missing. The leading model on its function proposes that DO inhibits the effects of DM. To directly study DO...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738515/ https://ncbi.nlm.nih.gov/pubmed/23951115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071228 |
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