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Selection of Immunodominant Epitopes During Antigen Processing is Hierarchical

MHC II proteins present processed antigens to CD4+ T cells through a complex set of events and players that include chaperons and accessory molecules. Antigen processing machinery is optimized for the selection of the best fitting peptides, called ‘immunodominant epitopes’, in the MHC II groove to w...

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Detalhes bibliográficos
Publicado no:Mol Immunol
Main Authors: Sadegh-Nasseri, Scheherazade, Kim, AeRyon
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387654/
https://ncbi.nlm.nih.gov/pubmed/30146122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2018.08.011
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