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Selection of Immunodominant Epitopes During Antigen Processing is Hierarchical

MHC II proteins present processed antigens to CD4+ T cells through a complex set of events and players that include chaperons and accessory molecules. Antigen processing machinery is optimized for the selection of the best fitting peptides, called ‘immunodominant epitopes’, in the MHC II groove to w...

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Dettagli Bibliografici
Pubblicato in:Mol Immunol
Autori principali: Sadegh-Nasseri, Scheherazade, Kim, AeRyon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387654/
https://ncbi.nlm.nih.gov/pubmed/30146122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2018.08.011
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