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Selection of Immunodominant Epitopes During Antigen Processing is Hierarchical

MHC II proteins present processed antigens to CD4+ T cells through a complex set of events and players that include chaperons and accessory molecules. Antigen processing machinery is optimized for the selection of the best fitting peptides, called ‘immunodominant epitopes’, in the MHC II groove to w...

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Vydáno v:Mol Immunol
Hlavní autoři: Sadegh-Nasseri, Scheherazade, Kim, AeRyon
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387654/
https://ncbi.nlm.nih.gov/pubmed/30146122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2018.08.011
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