Lataa...
Using Ligand-Based Virtual Screening to Allosterically Stabilize the Activated State of a GPCR
G-protein coupled receptors (GPCRs) play an essential role in many biological processes. Despite an increase in the number of solved X-ray crystal structures of GPCRs, capturing a GPCR in its activated state for structural analysis has proven to be difficult. An unexplored paradigm is stabilization...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911999/ https://ncbi.nlm.nih.gov/pubmed/20659113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2009.00944.x |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|