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Identification of Chemical Compounds that Induce HIF-1α Activity
Cellular metabolism depends on the availability of oxygen and the major regulator of oxygen homeostasis is hypoxia-inducible factor 1 (HIF-1), a highly conserved transcription factor that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF-1 is a heterodimeric tran...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910898/ https://ncbi.nlm.nih.gov/pubmed/19502547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp123 |
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