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The C-terminal α–α superhelix of Pat is required for mRNA decapping in metazoa
Pat proteins regulate the transition of mRNAs from a state that is translationally active to one that is repressed, committing targeted mRNAs to degradation. Pat proteins contain a conserved N-terminal sequence, a proline-rich region, a Mid domain and a C-terminal domain (Pat-C). We show that Pat-C...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910274/ https://ncbi.nlm.nih.gov/pubmed/20543818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.124 |
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