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Characterization of the Glu and Asp Residues in the Active Site of Human β-Hexosaminidase B

Human β-hexosaminidase A (αβ) and B (ββ) are composed of subunits (α and β) that are 60% identical and have been grouped with other evolutionarily related glycosidases into “Family 20”. The three-dimensional structure of only one Family 20 member has been elucidated, a bacterial chitobiase. This enz...

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Autori principali: Hou, Yongmin, Vocadlo, David J., Leung, Amy, Withers, Stephen G., Mahuran, Don
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910085/
https://ncbi.nlm.nih.gov/pubmed/11329289
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