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Role of βArg(211) in the Active Site of Human β-Hexosaminidase B
Tay–Sachs or Sandhoff disease results from a deficiency of either the α- or the β-subunits of β-hexosaminidase A, respectively. These evolutionarily related subunits have been grouped with the “Family 20” glycosidases. Molecular modeling of human hexosaminidase has been carried out on the basis of t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910084/ https://ncbi.nlm.nih.gov/pubmed/10821697 |
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