CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer’s disease-like pathogenesis in APP+PS1 bigenic mice

Cytokines play an emerging role as neurotransmitters, neuromodulators, and neurohormones in the brain. This paradigm shift in cytokine function offers a new framework to understand their roles in ameliorating neurodegenerative disorders, such as Alzheimer’s disease (AD). Molecular adjuvant therapy o...

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Detalhes bibliográficos
Main Authors: Kiyota, Tomomi, Okuyama, Satoshi, Swan, Russell J., Jacobsen, Michael T., Gendelman, Howard E., Ikezu, Tsuneya
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909296/
https://ncbi.nlm.nih.gov/pubmed/20371618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-155317
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