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Interferon-γ and Tumor Necrosis Factor-α Regulate Amyloid-β Plaque Deposition and β-Secretase Expression in Swedish Mutant APP Transgenic Mice

Reactive astrocytes and microglia in Alzheimer’s disease surround amyloid plaques and secrete proinflammatory cytokines that affect neuronal function. Relationship between cytokine signaling and amyloid-β peptide (Aβ) accumulation is poorly understood. Thus, we generated a novel Swedish β-amyloid pr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yamamoto, Masaru, Kiyota, Tomomi, Horiba, Masahide, Buescher, James L., Walsh, Shannon M., Gendelman, Howard E., Ikezu, Tsuneya
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851864/
https://ncbi.nlm.nih.gov/pubmed/17255335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060378
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