THE NEUROPHARMACOKINETICS OF TEMOZOLOMIDE IN PATIENTS WITH RESECTABLE BRAIN TUMORS: POTENTIAL IMPLICATIONS FOR THE CURRENT APPROACH TO CHEMORADIATION

PURPOSE: Intracerebral microdialysis (ICMD) is an accepted methodology for monitoring changes in neurochemistry from acute brain injury. The goal of this pilot study was to determine the feasibility of using ICMD to examine the neuropharmacokinetics (nPK) of temozolomide (TMZ) in brain interstitium...

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Detalhes bibliográficos
Main Authors: Portnow, Jana, Badie, Behnam, Chen, Mike, Liu, An, Blanchard, Suzette, Synold, Timothy W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908372/
https://ncbi.nlm.nih.gov/pubmed/19861433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1349
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