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IDENTIFICATION AND CHARACTERIZATION OF A NOVEL ENDOGENOUS MURINE PARKIN MUTATION
Various mutations in the PARK2 gene which encodes the protein, parkin, are causal of a disease entity termed autosomal recessive juvenile parkinsonism. Parkin can function as an E3 ubiquitin protein ligase, mediating the ubiquitination of specific targeted proteins and resulting in proteasomal degra...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908247/ https://ncbi.nlm.nih.gov/pubmed/20089136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06605.x |
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