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A Novel, High-Efficiency Cellular Model of Fibrillar α-Synuclein Inclusions and the Examination of Mutations that Inhibit Amyloid Formation
Intracytoplasmic alpha-synuclein (α-syn) amyloidogenic inclusions are a major pathological feature of Parkinson's disease, dementia with Lewy body disease, and multiple systems atrophy. The mechanisms involved in the formation and inhibition of these aggregates are areas of intense investigatio...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907888/ https://ncbi.nlm.nih.gov/pubmed/20132485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06592.x |
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