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Residue Glu83 Plays a Major Role in Negatively Regulating α-Synuclein Amyloid Formation

α-Synuclein (α-Syn) amyloid filaments are the major ultrastructural component of pathological inclusions that define several neurodegenerative disorders, including Parkinson disease and other disorders that are collectively termed synucleinopathies. Since the aggregation of α-syn is associated with...

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Hlavní autoři: Waxman, Elisa A., Emmer, Kristel L., Giasson, Benoit I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812690/
https://ncbi.nlm.nih.gov/pubmed/20026050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.12.079
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