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E46K Human α-Synuclein Transgenic Mice Develop Lewy-like and Tau Pathology Associated with Age-dependent, Detrimental Motor Impairment

Synucleinopathies are a group of neurodegenerative disorders associated with the formation of aberrant amyloid inclusions composed of the normally soluble presynaptic protein α-synuclein (α-syn). Parkinson disease is the most well known of these disorders because it bears α-syn pathological inclusio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Emmer, Kristel L., Waxman, Elisa A., Covy, Jason P., Giasson, Benoit I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186371/
https://ncbi.nlm.nih.gov/pubmed/21846727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.247965
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