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Induction of Intracellular Tau Aggregation Is Promoted by α-Synuclein Seeds and Provides Novel Insights into the Hyperphosphorylation of Tau

Intracytoplasmic proteinaceous inclusions, primarily composed of tau or α-synuclein (α-syn), are predominant pathological features of Alzheimer's disease (AD) and Parkinson's disease (PD), respectively. However, the coexistence of these pathological aggregates is identified in many neurode...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Waxman, Elisa A., Giasson, Benoit I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122484/
https://ncbi.nlm.nih.gov/pubmed/21613474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0297-11.2011
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