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Characterization of Hydrophobic Residue Requirements for α-Synuclein Fibrillization
α-Synuclein is the major component of pathological inclusions characteristic of diseases like Parkinson’s disease, dementia with Lewy bodies, and multiple systems atrophy. A role for α-synuclein in neurodegenerative diseases is further supported by point mutations and duplication/triplication of the...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758333/ https://ncbi.nlm.nih.gov/pubmed/19722699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900539p |
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