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Intradermal administration of RiVax protects mice from mucosal and systemic ricin intoxication

Ricin toxin is a CDC level B biothreat. We have developed a ricin vaccine, RiVax, which is a recombinant mutant of ricin A chain. RiVax is safe, immunogenic and protective in mice when administered intramuscularly (IM). We have now attempted to increase the utility and immunogenicity of RiVax by adm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marconescu, Praveena S., Smallshaw, Joan E., Pop, Laurentiu M., Ruback, Stephen L., Vitetta, Ellen S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908217/
https://ncbi.nlm.nih.gov/pubmed/20562013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.05.045
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