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Intradermal administration of RiVax protects mice from mucosal and systemic ricin intoxication
Ricin toxin is a CDC level B biothreat. We have developed a ricin vaccine, RiVax, which is a recombinant mutant of ricin A chain. RiVax is safe, immunogenic and protective in mice when administered intramuscularly (IM). We have now attempted to increase the utility and immunogenicity of RiVax by adm...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908217/ https://ncbi.nlm.nih.gov/pubmed/20562013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.05.045 |
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