Structural and Molecular Evolutionary Analysis of Agouti and Agouti-Related Proteins

Agouti (ASIP) and Agouti-related protein (AgRP) are endogenous antagonists of melanocortin receptors that play critical roles in the regulation of pigmentation and energy balance, respectively, and which arose from a common ancestral gene early in vertebrate evolution. The N-terminal domain of ASIP...

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Huvudupphovsmän: Jackson, Pilgrim J., Douglas, Nick R., Chai, Biaoxin, Binkley, Jonathan, Sidow, Arend, Barsh, Gregory S., Millhauser, Glenn L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907901/
https://ncbi.nlm.nih.gov/pubmed/17185225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2006.10.006
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