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Structural and Molecular Evolutionary Analysis of Agouti and Agouti-Related Proteins
Agouti (ASIP) and Agouti-related protein (AgRP) are endogenous antagonists of melanocortin receptors that play critical roles in the regulation of pigmentation and energy balance, respectively, and which arose from a common ancestral gene early in vertebrate evolution. The N-terminal domain of ASIP...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907901/ https://ncbi.nlm.nih.gov/pubmed/17185225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2006.10.006 |
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