Structural and Molecular Evolutionary Analysis of Agouti and Agouti-Related Proteins

Agouti (ASIP) and Agouti-related protein (AgRP) are endogenous antagonists of melanocortin receptors that play critical roles in the regulation of pigmentation and energy balance, respectively, and which arose from a common ancestral gene early in vertebrate evolution. The N-terminal domain of ASIP...

Full description

Saved in:
Bibliographic Details
Main Authors: Jackson, Pilgrim J., Douglas, Nick R., Chai, Biaoxin, Binkley, Jonathan, Sidow, Arend, Barsh, Gregory S., Millhauser, Glenn L.
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907901/
https://ncbi.nlm.nih.gov/pubmed/17185225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2006.10.006
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items