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Genome-Wide Association Studies and the Problem of Relatedness Among Advanced Intercross Lines and Other Highly Recombinant Populations

Model organisms offer many advantages for the genetic analysis of complex traits. However, identification of specific genes is often hampered by a lack of recombination between the genomes of inbred progenitors. Recently, genome-wide association studies (GWAS) in humans have offered gene-level mappi...

詳細記述

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書誌詳細
主要な著者: Cheng, Riyan, Lim, Jackie E., Samocha, Kaitlin E., Sokoloff, Greta, Abney, Mark, Skol, Andrew D., Palmer, Abraham A.
フォーマット: Artigo
言語:Inglês
出版事項: Genetics Society of America 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907190/
https://ncbi.nlm.nih.gov/pubmed/20439773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.116863
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