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QTLRel: an R Package for Genome-wide Association Studies in which Relatedness is a Concern

BACKGROUND: Existing software for quantitative trait mapping is either not able to model polygenic variation or does not allow incorporation of more than one genetic variance component. Improperly modeling the genetic relatedness among subjects can result in excessive false positives. We have develo...

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Bibliografiske detaljer
Main Authors: Cheng, Riyan, Abney, Mark, Palmer, Abraham A, Skol, Andrew D
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160955/
https://ncbi.nlm.nih.gov/pubmed/21794153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-12-66
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