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Genome-Wide Association Studies and the Problem of Relatedness Among Advanced Intercross Lines and Other Highly Recombinant Populations

Model organisms offer many advantages for the genetic analysis of complex traits. However, identification of specific genes is often hampered by a lack of recombination between the genomes of inbred progenitors. Recently, genome-wide association studies (GWAS) in humans have offered gene-level mappi...

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Hlavní autoři: Cheng, Riyan, Lim, Jackie E., Samocha, Kaitlin E., Sokoloff, Greta, Abney, Mark, Skol, Andrew D., Palmer, Abraham A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907190/
https://ncbi.nlm.nih.gov/pubmed/20439773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.116863
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