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Genome-Wide Association Studies and the Problem of Relatedness Among Advanced Intercross Lines and Other Highly Recombinant Populations

Model organisms offer many advantages for the genetic analysis of complex traits. However, identification of specific genes is often hampered by a lack of recombination between the genomes of inbred progenitors. Recently, genome-wide association studies (GWAS) in humans have offered gene-level mappi...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Cheng, Riyan, Lim, Jackie E., Samocha, Kaitlin E., Sokoloff, Greta, Abney, Mark, Skol, Andrew D., Palmer, Abraham A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Genetics Society of America 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907190/
https://ncbi.nlm.nih.gov/pubmed/20439773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.116863
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