Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice

Leptin-deficient ob/ob mice are overweight, develop insulin resistance, and serve as a model for type 2 diabetes (T2D). Studies suggest that inflammatory pathways are linked to the development of insulin resistance and T2D both in animals and humans. We asked whether the induction of regulatory T ce...

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Main Authors: Ilan, Yaron, Maron, Ruth, Tukpah, Ann-Marcia, Maioli, Tatiani Uceli, Murugaiyan, Gopal, Yang, Kaiyong, Wu, Henry Yim, Weiner, Howard L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906892/
https://ncbi.nlm.nih.gov/pubmed/20445103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908771107
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