Purified Plasmodium falciparum Multi-Drug Resistance Protein (PfMDR 1) Binds a High Affinity Chloroquine Analogue

We utilize the recent successful overexpression of recombinant Plasmodium falciparum multidrug resistance transporter, purification and reconstitution of the protein, and a novel high affinity chloroquine analogue to probe hypothesized interaction between the transporter and quinoline drugs. Results...

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Bibliographic Details
Main Authors: Pleeter, Perri, Lekostaj, Jacqueline K., Roepe, Paul D.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906614/
https://ncbi.nlm.nih.gov/pubmed/20546803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.05.012
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الانترنت

https://ncbi.nlm.nih.gov/pmc/articles/PMC2906614/
https://ncbi.nlm.nih.gov/pubmed/20546803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.05.012

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