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Purified Plasmodium falciparum Multi-Drug Resistance Protein (PfMDR 1) Binds a High Affinity Chloroquine Analogue
We utilize the recent successful overexpression of recombinant Plasmodium falciparum multidrug resistance transporter, purification and reconstitution of the protein, and a novel high affinity chloroquine analogue to probe hypothesized interaction between the transporter and quinoline drugs. Results...
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Main Authors: | , , |
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格式: | Artigo |
語言: | Inglês |
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2010
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906614/ https://ncbi.nlm.nih.gov/pubmed/20546803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.05.012 |
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