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Photoaffinity Labeling of the Plasmodium falciparum Chloroquine Resistance Transporter with a Novel Perfluorophenylazido Chloroquine

Several models describing how amino acid substitutions in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) confer resistance to chloroquine (CQ) and other antimalarial drugs have been proposed. Further progress requires molecular analysis of interactions between purified reconsti...

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Detalhes bibliográficos
Main Authors: Lekostaj, Jacqueline K., Natarajan, Jayakumar K., Paguio, Michelle F., Wolf, Christian, Roepe, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724749/
https://ncbi.nlm.nih.gov/pubmed/18767816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8010658
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