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Photoaffinity Labeling of the Plasmodium falciparum Chloroquine Resistance Transporter with a Novel Perfluorophenylazido Chloroquine

Several models describing how amino acid substitutions in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) confer resistance to chloroquine (CQ) and other antimalarial drugs have been proposed. Further progress requires molecular analysis of interactions between purified reconsti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lekostaj, Jacqueline K., Natarajan, Jayakumar K., Paguio, Michelle F., Wolf, Christian, Roepe, Paul D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724749/
https://ncbi.nlm.nih.gov/pubmed/18767816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8010658
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