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Purified Plasmodium falciparum Multi-Drug Resistance Protein (PfMDR 1) Binds a High Affinity Chloroquine Analogue
We utilize the recent successful overexpression of recombinant Plasmodium falciparum multidrug resistance transporter, purification and reconstitution of the protein, and a novel high affinity chloroquine analogue to probe hypothesized interaction between the transporter and quinoline drugs. Results...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906614/ https://ncbi.nlm.nih.gov/pubmed/20546803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.05.012 |
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