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Chloroquine Transport in Plasmodium falciparum II: Analysis of PfCRT Mediated Drug Transport Using Proteoliposomes and a Fluorescent Chloroquine Probe

Mutations in the PfCRT protein cause chloroquine resistance (CQR) and earlier studies from our laboratory using plasma membrane inside-out vesicles (ISOV) prepared from yeast expressing recombinant PfCRT [Zhang, H., et al. (2004) Biochemistry 43, 8290–8296] suggested that the putative transporter me...

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Bibliografski detalji
Glavni autori: Paguio, Michelle F., Cabrera, Mynthia, Roepe, Paul D.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778255/
https://ncbi.nlm.nih.gov/pubmed/19725576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901035j
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