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Chloroquine Transport in Plasmodium falciparum II: Analysis of PfCRT Mediated Drug Transport Using Proteoliposomes and a Fluorescent Chloroquine Probe
Mutations in the PfCRT protein cause chloroquine resistance (CQR) and earlier studies from our laboratory using plasma membrane inside-out vesicles (ISOV) prepared from yeast expressing recombinant PfCRT [Zhang, H., et al. (2004) Biochemistry 43, 8290–8296] suggested that the putative transporter me...
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Autors principals: | , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2009
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778255/ https://ncbi.nlm.nih.gov/pubmed/19725576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901035j |
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