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Chloroquine Transport in Plasmodium falciparum I: Influx and Efflux Kinetics for Live Trophozoite Parasites using a Novel Fluorescent Chloroquine Probe

Several models for how amino acid substitutions in the Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) confer resistance to chloroquine (CQ) and other antimalarial drugs have been proposed. Distinguishing between these models requires detailed analysis of high resolution CQ transpor...

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Detalhes bibliográficos
Main Authors: Cabrera, Mynthia, Natarajan, Jayakumar, Paguio, Michelle F., Wolf, Christian, Urbach, Jeffrey S., Roepe, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765664/
https://ncbi.nlm.nih.gov/pubmed/19728740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901034r
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