Destabilization of the A1 Domain in von Willebrand Factor Dissociates the A1A2A3 Tri-domain and Provokes Spontaneous Binding to Glycoprotein Ibα and Platelet Activation under Shear Stress

Lignende værker

• N-terminal Flanking Region of A1 Domain in von Willebrand Factor Stabilizes Structure of A1A2A3 Complex and Modulates Platelet Activation under Shear Stress
  af: Auton, Matthew, et al.
  Udgivet: (2012)
• A molten globule intermediate of the Von Willebrand Factor A1 domain firmly tethers platelets under shear flow
  af: Tischer, Alexander, et al.
  Udgivet: (2013)
• Von Willebrand factor-A1 domain binds platelet glycoprotein Ibα in multiple states with distinctive force-dependent dissociation kinetics
  af: Ju, Lining, et al.
  Udgivet: (2015)
• Platelet Glycoprotein Ibβ/IX Mediates Glycoprotein Ibα Localization to Membrane Lipid Domain Critical for von Willebrand Factor Interaction at High Shear
  af: Geng, Hongquan, et al.
  Udgivet: (2011)
• Mechanisms by which von Willebrand Disease Mutations Destabilize the A2 Domain
  af: Xu, Amy J., et al.
  Udgivet: (2013)