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S-Adenosylmethionine Regulates Dual-Specificity Mitogen-Activated Protein Kinase Phosphatase Expression in Mouse and Human Hepatocytes

Increased mitogen-activated protein kinase (MAPK) activity correlates with a more malignant hepatocellular carcinoma (HCC) phenotype. There is a reciprocal regulation between p44/42 MAPK (extracellular signal-regulated kinase [ERK]1/2) and the dual-specificity MAPK phosphatase MKP-1/DUSP1. ERK phosp...

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Bibliographische Detailangaben
Hauptverfasser: Tomasi, Maria Lauda, Ramani, Komal, Lopitz-Otsoa, Fernando, Rodríguez, Manuel S., Li, Tony W. H., Ko, Kwangsuk, Yang, Heping, Bardag-Gorce, Fawzia, Iglesias-Ara, Ainhoa, Feo, Francesco, Pascale, Maria Rosa, Mato, José M., Lu, Shelly C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905543/
https://ncbi.nlm.nih.gov/pubmed/20196119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23530
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